I have the following math block in a README.md:

begin{split}
    frac{partial Q_0}{partial Lambda_0}
    &=
    frac{I_{0}^{2} Lambda_{0}^{4} + I_{0}^{2} Lambda_{0}^{2} Lambda_{1}^{2} - I_{0} I_{1} Lambda_{0}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}} + I_{0} I_{1} Lambda_{1}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}} - I_{1}^{2} Lambda_{0}^{4} - I_{1}^{2} Lambda_{0}^{2} Lambda_{1}^{2}}{I_{0}^{2} left(Lambda_{0}^{2} + Lambda_{1}^{2}right)^{2}} \
    frac{partial Q_1}{partial Lambda_0}
    &=
    frac{Lambda_{0} Lambda_{1} left(I_{0}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}} - 2 I_{0} I_{1} - I_{1}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}}right)}{I_{0}^{2} left(Lambda_{0}^{2} + Lambda_{1}^{2}right)^{frac{3}{2}}} \
    frac{partial Q_0}{partial Lambda_1}
    &=
    frac{Lambda_{0} Lambda_{1} left(I_{0}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}} - 2 I_{0} I_{1} - I_{1}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}}right)}{I_{0}^{2} left(Lambda_{0}^{2} + Lambda_{1}^{2}right)^{frac{3}{2}}} \
    frac{partial Q_1}{partial Lambda_1}
    &=
    frac{I_{0}^{2} Lambda_{0}^{2} Lambda_{1}^{2} + I_{0}^{2} Lambda_{1}^{4} + I_{0} I_{1} Lambda_{0}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}} - I_{0} I_{1} Lambda_{1}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}} - I_{1}^{2} Lambda_{0}^{2} Lambda_{1}^{2} - I_{1}^{2} Lambda_{1}^{4}}{I_{0}^{2} left(Lambda_{0}^{2} + Lambda_{1}^{2}right)^{2}}
end{split}

When I use Pandoc with gfm formatting, it renders, but on the GitHub preview it says Unable to render expression. I’ve tried trimming it down to identify the problem, but even when I change a symbol from Lambda_{0}^{2} to Lambda_0^2 it seems to affect whether it is rendered or not.

How should I go about debugging this?

Edit 1: At the suggestion of the comments, I’ve removed everything that I can while still reproducing the problem. Unfortunately it seems that the first two lines need to remain the same, and I can only partially reduce the third line:

begin{split}
    frac{partial Q_0}{partial Lambda_0}
    &=
    frac{I_{0}^{2} Lambda_{0}^{4} + I_{0}^{2} Lambda_{0}^{2} Lambda_{1}^{2} - I_{0} I_{1} Lambda_{0}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}} + I_{0} I_{1} Lambda_{1}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}} - I_{1}^{2} Lambda_{0}^{4} - I_{1}^{2} Lambda_{0}^{2} Lambda_{1}^{2}}{I_{0}^{2} left(Lambda_{0}^{2} + Lambda_{1}^{2}right)^{2}} \
    frac{partial Q_1}{partial Lambda_0}
    &=
    frac{Lambda_{0} Lambda_{1} left(I_{0}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}} - 2 I_{0} I_{1} - I_{1}^{2} sqrt{Lambda_{0}^{2} + Lambda_{1}^{2}}right)}{I_{0}^{2} left(Lambda_{0}^{2} + Lambda_{1}^{2}right)^{frac{3}{2}}} \
    frac{partial Q_0}{partial Lambda_1}
    &=
    frac{I_{0}^{2} sqrt{Lambda_{0}^{2}}}{I_{0}^{2} left(Lambda_{0}^{2} + Lambda_{1}^{2}right)^{frac{3}{2}}}
end{split}

Any other terms that I remove cause it to be correctly rendered.