Searching in the web and in Stack Overflow I didn’t find post where the problem was solved
I’ve this code
$params = array();
$file = new Google_Service_Drive_DriveFile();
$file->setProperties("myProp"=>null);
$response = $driveService->files->update($fileid,$file,$params);
and has no effect… the property mantains its original value (set with the same method)