I have been working with the PlotPy library (not to be confused with Plotly) to create a Python Qt GUI to display a series of plots — one of which happens to be a 2D Histogram. Following their example with some modifications to the data, I was able to create a Histogram2DItem that displays 150,000 dots on a scatter plot that appear within the X values of 0.57-13.57 and the Y values of 1.59-15.46 (rounded to the nearest hundredth).