When using Anaconda to create and manage Python environments, noticed multiple cases when it was very easy to activate and damage Anaconda base environment by an accident.
This leads to Navigator update and functional corruptions, multiple GB base env which are unused, and also may lead to full reinstall which in some complex cases _{(for example, one package installs only with pip and another only with conda, but both required)} may take hours to figure out correct versions for conflicting packages.