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How can I use the WebMidi API to send SYSYEX messages to a device on Windows?

I am building an app that uses the WebMidi API to send and receive messages from a MIDI device that is connected via USB. Currently the app works perfectly on MacOS, but not on Windows machines. The device is successfully identified/detected and permissions are granted, however – when I attempt to send a Sysex message to the device on a Windows machine, the screen just flickers. The midi message appears to be sending, and the device is receiving data, but the settings that should be affected as part of the message are not changing…just screen flicker each time I send over data.