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How to plot multiple data sets imported from excel worksheet in matplotlib?

I need help with plotting the data from excel into matplotlib. The data is taken from one worksheet. The columns have similar structure:column a -x values, column b – y values, column c – x values, d – y values etc.. I want python to loop through the data set and plot it in separate plots. Also I want to learn how to combine multiple data sets in one plot. Here is what I managed so far: