During my CODA software, I found that I cannot annotate the TIFF files generated with ImageScope, and I am having trouble training the model correctly. Can you please give me more guidance? Thank you very much.
Firstly, I followed the steps(https://labs.pathology.jhu.edu/kiemen/wp-content/uploads/sites/39/2023/12/Instructions-for-applying-CODA.pdf
，download data from https://drive.google.com/drive/folders/1K-wY_ArVGbEhebQD4AjOeERwx6-4Fw3G),
but the generated TIF file cannot be opened in ImageScope. I have downloaded the latest version of ImageScope. just like this（Attachment 1）:
enter image description here

Then,secondly, the TIF file generated by downsampling with OpenSlide also encountered issues when annotating cell types.

here is a more organized and clear description of your script using OpenSlide to produce a downsampled TIFF file:

from PIL import Image
import numpy as np

slide = openslide.OpenSlide('lungs_001-.ndpi')

target_mpp = 1.0 #

current_mpp_x = float(slide.properties[openslide.PROPERTY_NAME_MPP_X])
current_mpp_y = float(slide.properties[openslide.PROPERTY_NAME_MPP_Y])

scale_factor_x = current_mpp_x / target_mpp
scale_factor_y = current_mpp_y / target_mpp

level = slide.get_best_level_for_downsample(scale_factor_x)
downsample = slide.level_downsamples[level]

region = slide.read_region((0, 0), level, slide.level_dimensions[level])

region_rgb = region.convert("RGB")

region_np = np.array(region_rgb)

width, height = region.size
scaled_width = int(width * scale_factor_x)
scaled_height = int(height * scale_factor_y)

scaled_image = Image.fromarray(region_np).resize((scaled_width, scaled_height), Image.LANCZOS)

scaled_image.save('output_file.tiff', format='TIFF')

slide.close()

just like this（Attachment 2）:
enter image description here