I created an object:

class Button : public QObject, public QGraphicsPixmapItem
{
    Q_OBJECT

next I implemented a few functions:

Button::Button()
    : m_pressed(false)
{
    m_buttonPixmap = PixmapManager::Instance()->getPixmap(PixmapManager::Button);
    m_pressedButtonPixmap = PixmapManager::Instance()->getPixmap(PixmapManager::PressedButton);
    setFlags(QGraphicsItem::ItemIsSelectable | QGraphicsItem::ItemIsFocusable);
}

QRectF Button::boundingRect() const
{
    return QRectF(-m_buttonPixmap.width() / 2.0f,
                  -m_buttonPixmap.height() / 2.0f,
                  m_buttonPixmap.width(),
                  m_buttonPixmap.height());

}

void Button::paint(QPainter *painter, const QStyleOptionGraphicsItem *option, QWidget *widget)
{
    if (m_pressed) {
        //painter->drawPixmap(0,0, m_pressedButtonPixmap);

    }
    else {
        painter->setBrush(Qt::red);
        painter->drawRect(boundingRect());
        //painter->drawPixmap(0,0, m_buttonPixmap);
    }
}

void Button::mousePressEvent(QGraphicsSceneMouseEvent *event)
{
    qDebug() << "pressed ";
    m_pressed = true;
    update();
    QGraphicsPixmapItem::mousePressEvent(event);
}

void Button::mouseReleaseEvent(QGraphicsSceneMouseEvent *event)
{
    qDebug() << "released ";
    m_pressed = false;
    update();
    QGraphicsPixmapItem::mouseReleaseEvent(event);
}

I also created a QGraphicsScene with Button item:

MenuScene::MenuScene(QObject *parent)
    : QGraphicsScene(parent)
{
    setSceneRect(0,0, SCREEN::PHYSICAL_SIZE.width(), SCREEN::PHYSICAL_SIZE.height());
    addItem(&m_startButton);
}

void MenuScene::mousePressEvent(QGraphicsSceneMouseEvent *event)
{
    qDebug() << "Scene pressed";
    QGraphicsScene::mousePressEvent(event);
}

void MenuScene::mouseReleaseEvent(QGraphicsSceneMouseEvent *event)
{
    qDebug() << "Scene released";
    QGraphicsScene::mouseReleaseEvent(event);
}

If I click on a button I got only information from MenuScene like “Scene pressed”/”Scene released”

I tried use:
m_startButton.setAcceptedMouseButtons(Qt::AllButtons);
m_startButton.setFlags(QGraphicsItem::ItemIsSelectable | QGraphicsItem::ItemIsFocusable);
but without result.