Is it possible to compare the JMeter response from the previous run with the one being run now, and then add a rule set to remove a specific key or param from the response while comparing both the response using JMeter plugin?

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I’ve tried using the comparison assertion, which is a complicated method since if we enter a regex pattern incorrectly, the case fails overall and we don’t know in which point it fails. Moreover, by doing this, we are unable to compare previously and currently ran.